On the other hand, carbapenem resistant E. Transferable carbapenem-resistance was studied in 11 isolates producing MBLs belonging to the VIM-lineage, derived from four European countries. Similarly, virulence factors were highly found in carbapenem susceptible isolates, shows that other mechanisms may have an effect on the relation between carbapenem resistance and virulence. The most important virulence factors for urinary tract infections are fimbriae. International Journal of Antimicrobial Agents ; Data analysis The Fisher’s Exact Test were performed for all clinical data.

Therefore, determining of beta-lactam group resistance, these mechanisms should be taken into consideration. Infection and Immunity ; Search and download doctoral PHD dissertations from Sweden. Down-regulation of OprD, which is the primary porin for carbapenem uptake, confers resistance to both imipenem and meropenem, although the latter is affected less. Production by Escherichia coli isolates of siderophore and other virulence factors and their pathogenic role in a cutaneous infection model. OmpC and the sigma E regulatory pathway are involved in adhesion and invasion of the Crohn’s disease-associated Escherichia coli strain LF Existing mechanisms are mainly due to acquired carbapenemases or the combination of ESBL-production and reduced outer membrane permeability.

Carbapenemase; Escherichia coli; multiplex polymerase chain reaction; virulence factor. Also, the frequency of virulence gene regions in E. DNA sequence analysis of the composite plasmid pTC conferring virulence and antimicrobial resistance for porcine enterotoxigenic Escherichia coli. Analysis of a carbapenem hydrolyzing class A b-lactamase from Enterobacter cloacae and of its LysR-type regulatory protein.

Another virulence gene region found with high incidence in our study was fimA which is related to Type I fimbriae. Virulence genes in verocytotoxigenic Escherichia coli strains isolated from humans and cattle.

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carbapenem resistance dissertation

Carbapenem gene regions of these isolates are given in Figure 1. Clinical Microbiology and Infection ; International Journal of Antimicrobial Agents ;31, On the other hand similar result were reported in our study. Searchphrases right now project management change management computer support Otto H.

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carbapenem resistance dissertation

Acta Universitatis Upsaliensis Author: In this study, fifty Escherichia coli strains were analyzed by multiplex polymerase chain reaction for the genes expressed carbapenemase and virulence factors in order to determine the presence of carbapenemase and nine virulence factors and investigate the association between these two characteristics. In this study, nine virulence gene regions pap, afa, fimA, sfa, hly, iroN, aer, cnf-1 and iutA for E.

The aim of this thesis was to study chromosomal and transferable carbapenemresistance in clinical isolates of P. Indian Journal of Microbiology ; Search and download doctoral PHD dissertations from Sweden. African Journal of Microbiology Research ;6: Existing mechanisms are mainly due to acquired carbapenemases or the combination of ESBL-production and reduced outer membrane permeability.

Escherichia Coli: Characteristics of Carbapenem Resistance and Virulence Factors

February 03, ; Accepted: The distribution of the virulence gene regions in E. The data of this study have been excerpted from the PhD thesis of the author. Similarly, in Johnson et al. Escherichia coli virulence factors. Current issues in the management of urinary tract infections: The mix for the detection of other groups afa-sfa-fimA, hly-iroN-aer-cnf1-iutA was at the same concentrations. DNA sequencing of oprD, pbp-2, pbp-3 and some of the efflux pump regulatory genes was conducted in selected isolates.

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Search for dissertations about: “carbapenem resistant enterobacteriaceae”

Clinical Microbiology Reviews ; Transferable carbapenem-resistance was studied in 11 isolates producing MBLs belonging to the VIM-lineage, derived from four European countries.

Found 3 swedish dissertations containing the words carbapenem resistant enterobacteriaceae.

carbapenem resistance dissertation

Analysis of the virulence resitsance regions In this study, nine virulence gene regions pap, afa, fimA, carbapenm, hly, iroN, aer, cnf-1 and iutA for E. This is an open-access article distributed under the terms of the Creative Commons Attribution License.

International Journal of Antimicrobial Agents ; ABSTRACT In this study, fifty Escherichia coli strains were analyzed by multiplex polymerase chain reaction for the genes expressed carbapenemase and virulence factors in order to determine the presence of carbapenemase and nine virulence factors and investigate the association between these two characteristics.

Revista Latino-Americana de Enfermagem ; Apart from alterations of OprD and the efflux pumps, changes of penicillin-binding proteins have been suggested resistancd a third chromosomal mechanism of carbapenem resistance.